Ren-Hua Chung, PhD


hua-chung-web.jpgRen-Hua Chung, PhD, is a Research Assistant Professor in the Miami Institute for Human Genetics. Dr. Chung is a statistical geneticist who is interested in statistical method development for complex disease-gene mapping. He extended the Association in the Presence of Linkage (APL) method to general nuclear family structures and haplotype analyses. He also developed APL-OSA, which applied the Ordered Subset Analysis to APL. His current research interests focus on the development of an association test that can use both family and case-control data and also the development of family-based association test for X-linked analyses.





Contact
rchung@med.miami.edu
Research Assistant Professor
Miami Institute for Human Genomics
Tel: 305-243-4579
Fax: 305-243-2396

Selected Publications
  1. Chung R-H, Schmidt S, Martin ER, Hauser ER (2008) Ordered subset analysis (OSA) for family-based association mapping of complex traits. Genetic Epidemiology. In press.
  2. Chung R-H, Morris RW, Martin ER (2007) Response to "XMCPDT does have correct type I error rates" by Jie Ding and Shili Lin. The American Journal of Human Genetics. 82(2):530-531.
  3. Zhang L, Martin ER, Chung R-H, Li Y-J, Morris RW (2007) X-LRT: A likelihood approach to estimate genetic risks and test association with X-linked markers using a case-parents design. Genetic Epidemiology. 32(4):370-380.
  4. Chung R-H, Morris RW, Zhang L, Li Y-J, Martin ER (2007) X-APL: An improved family-based test of association for the X chromosome. The American Journal of Human Genetics. 80(1): 59-68.
  5. Chung R-H, Hauser ER, Martin ER (2007) Interpretation of simultaneous linkage and family-based association tests in genome screens. Genetic Epidemiology. 31:134-142.
  6. Chung R-H, Hauser ER, Martin ER (2006) The APL test: Extension to general nuclear families and haplotypes and examination of its robustness. Human Heredity. 61(4):189-99.
  7. Martin ER, Bronson PG, Li YJ, Wall N, Chung R-H, Schmechel DE, Small G, Xu PT, Bartlett J, Schnetz-Boutaud N, Haines JL, Gilbert JR, Pericak-Vance MA (2005) Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease. Journal of Medical Genetics. 42(10):787-92.
  8. Chung R-H, Gusfield D (2003) Perfect phylogeny haplotyper: haplotype inferral using a tree model. Bioinformatics. 19(6): 780-781.