Richard W. Morris


Photo morris_r_web_resize.jpgRichard W. Morris, Ph.D trained as a statistical geneticist with Dr. Norman Kaplan and currently studies statistical methods for identifying the genetic basis of complex diseases. He has contributed to theoretical studies of linkage disequilibrium in admixed populations, to genetic association methods for X-linked markers, and to the utility of haplotypes as markers of complex disease genes. He has also studied haplotype structure using high-density SNP data from resequenced genes, and has collaborated with physicians on genetic association studies of a variety of adverse clinical outcomes following coronary artery by-pass surgery. He is currently the Associate Director of the Center for Genetic Epidemiology and Statistical Genetics at the MIHG




Contact Information
rmorris@med.miami.edu
Assistant: Lili Tewes
Miami Institute for Human Genomics
1120 NW 14th Street
Miami, FL 33136
ph: 305-243-5391
fax: 305-243-2396

Selected Publications

  1. Kaplan NL, Morris RW (2001). Prospects for association-based fine mapping of a susceptibility gene for a complex disease. Theor Pop Biol 60:181-191
  2. Kaplan NL, Morris RW (2001). Issues concerning association studies for fine mapping a susceptibility gene for a complex disease. Genetic Epidem 20: 432-457
  3. Kaplan NL, Morris RW (2002). Comment on "Adjusting for population heterogeneity and misspecified haplotype frequencies when testing nonparametric null hypotheses in statistical genetics" by D Rabinowitz. J Amer Stat Assoc 97:753-754
  4. Morris RW, Kaplan NL (2002). On the advantage of haplotype analysis in the presence of multiple susceptibility alleles. Genetic Epidem 23:221-233
  5. Orelien JG, Zhai J, Morris RW, Cohn R (2002). An approach to performing multiple comparisons with a control in GEE models. Communications in Statistics—Theory and Methods 1: 87-105
  6. Weinberg CR, Morris RW (2003). Commentary regarding testing for Hardy-Weinberg disequilibrium using a genome SNP scan based on cases only. Am J Epidem 158:401-403
  7. David GL, Romieu I, Sienra-Monge JJ, Collins WJ, Ramirez-Aguilar M, del Rio-Navarro BL, Reyes-Ruiz NI, Morris RW, Marzec JM, London SJ (2003). NQO1 and GSTM1 polymorphisms and childhood asthma in a high ozone area: Mexico City. Am J Respir Crit Care Med 168:199-1204
  8. Morris RW, Kaplan NL (2004). Testing for association with a case-parent design in the presence of genotyping errors. Genetic Epidem 26(2):142-154
  9. Zhai, J, Morris RW (2005). A Markov chain model for animal estrous cycling data. Biometrics 61(1):141-150
  10. Stafford-Smith M, Podgoreanu M, Swaminathan M, Barbara Phillips-Bute B, Mathew JP, Hauser EH, Winn MP, Milano C, Nielsen DM, Smith M, Morris R, Newman MF, Schwinn DA (2005). Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery. Am J Kidney Diseases. 45(3): 519-530
  11. Grocott HP, White WD, Morris RW, Podgoreanu M, Mathew JP, Nielsen DM, Schwinn DA, Newman MF (2005). Genetic polymorphisms and the risk of stroke after cardiac surgery. Stroke. 36:1854-1858
  12. Moretti EW, Morris RW, Podgoreanu M, Schwinn DA, Newman MF, Bennett E, Moulin VG, Mba UU, Laskowitz DT (2005). APOE polymorphism is associated with risk of severe sepsis in surgical patients. Crit Care Med. 33(11):2521-2526
  13. Taylor JA, Xu Z-L, Kaplan NL, Morris RW (2006). How Well Do HapMap Haplotypes Identify Common Haplotypes of Genes? A Comparison with Haplotypes of 334 Genes Resequenced in the Environmental Genome Project. Can. Epid. Bio. Prev. 15(1):133-137
  14. Podgoreanu MV, White WD, Morris RW, Mathew JP, Stafford-Smith M, Welsby IJ, Grocott HP, Milano CA, Newman MF, Schwinn DA. (2006). Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery. Circulation 114: 275-281
  15. Rampersaud E, Morris RW, Weinberg CR, Speer MC, Martin ER. (2007). Power calculations of likelihood ratio tests for offspring genotype risks, maternal effects and parent-of-origin (POO) effects in the presence of missing parental genotypes when unaffected siblings are available. Genetic Epidemiology 31(1): 18-30.
  16. Chung RH, Morris RW, Zhang L, Li YJ, Martin ER. (2007). X-APL: An improved family-based test of association in the presence of linkage for the X chromosome. American J Human Genetics 80:59-68.
  17. Shi M, Christensen K, Weinberg CR, Romitti P, Bathum L, Lozada A, Morris RW, Lovett M, Murray JC. (2007). Orofacial cleft risk is increased with maternal smoking and specific detoxification gene variants. American J Human Genetics 80:76-90.
  18. Mathew JP, Podgoreanu MV, Grocott HP, White WD, Morris RW, Stafford-Smith M, Mackensen GB, Rinder CS, Blumenthal JA, Schwinn DA, Newman MF (2007). Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery. (J American College of Cardiology 49(19):1934-42).
  19. Zhang L, Li Y-J, Chung RH, Martin ER, Morris RW (2008) X-LRT: A likelihood approach to estimate genetic risks and test association with x-linked markers using a case-parents design. Genetic Epidemiology. May; 32(4):370-380.