John R Gilbert


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John R. Gilbert, PhD, is a Professor of Human Genetics and Director of the Center for Genome Technology at MIHG. Dr. Gilbert's research focuses on applications of genome technology to human genetics and the molecular genetics of autism, Alzheimer disease, Essential Tremor, and infectious disease (TB). As a molecular biologist, his expertise is in gene analysis and characterization, positional cloning, mutation analysis, and animal models of human disorders.





Contact Information
jgilbert@med.miami.edu
Miami Institute for Human Genomics
1120 NW 14th Street
Miami, FL 33136
ph: 305-243-6177
fax: 305-243-2396

Selected Publications

  1. Schmidt S, Postel EA, Agarwal A, Allen Jr. IC, De La Paz MA, Scott WK, Haines JL, Pericak-Vance MA, Gilbert JR. Detailed analysis of allelic variation in the ABCA4 gene in age-related maculopathy. Investigative Ophthalmology and Visual Sciences 2003 Jul; 44(7): 2868-2875.
  2. Li Y-J, Oliveria SA, Xu PT, Martin ER, Stenger JE, Scherzer CR, Hauser MA, Scott WK, Small GW, Nance MA, Watts, RL, Hubble JP, Koller WC, Pahwa R, Roses D, Saunders AM, Schmechel DE, Gullans SR Haines JL, Gilbert JR, Vance JM, Pericak-Vance MA. Glutathione S-Transferase Omega 1 modifies age-at-onset of Alzheimer Disease. Human Molecular Genetics 2003 Dec15; 12(24):3259-67
  3. Deak KL, Boyles AL, Etchevers HC, Melvin EC, Siegel DG, Graham FL, Slifer S, Enterline DS, George TM, Vekemans M, McClay D, Bassuk AG, Kessler JA, Linney E, Gilbert JR, Speer MC, and the NTD Collaborative Group* SNPs in the Neural Cell Adhesion Molecule 1 (NCAM1) may be Associated with Human Neural Tube Defects. Hum Genet. 2005 Jul; 117(2-3):133-42.
  4. Ma DQ, Whitehead PL, Menold MM, Martin ER, Ashley-Koch AE, Mei H, Ritchie MD, DeLong MR, Abramson RK, Wright HH, Cuccaro ML, Hussman JP, Gilbert JR, Pericak-Vance MA. Identification of significant association and gene-gene interaction on GABA receptor subunit genes in autism. Am J Hum Genet 2005 Sept; 77(3):377-388.
  5. Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine M, Gilbert JR, Schnetz-Boutaud N, Agarwal A, Postel EA, Pericak-Vance MA. Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration. Science. 2005; 308: 419-42.
  6. Bastress KL, Stajich JM, Speer MC, Gilbert JR. The genes encoding for D4Z4 binding proteins HMGB2, YY1, NCL, and MYOD1 are excluded as candidate genes for FSHD1B. Neuromuscular Disord. 2005; 15(4):316-20.
  7. Xu P, Li Y-J, Qin XJ, Scherzer CR, Xu H, Schmechel DE, Hulette CM, Ervin J, Gullans SR, Haines J, Pericak-Vance MA, Gilbert JR. Differences in Apolipoprotein E3/3 and E4/4 Allele-Specific Gene Expression in Hippocampus in Alzheimer Disease. Neurobiol Dis 2006.Feb; 21(2):256-75.
  8. J Deak KL, Lemmers R JLF, Stajich JM, Tawil, R, Frants RR, Speer MC, van der Maarel SM, Gilbert JR. Genotype-phenotype study in an FSHD family with a proximal deletion encompassing p13E-11 and D4Z4. Neurology. 2007; 68; 578-582.
  9. The Autism Genome Project Consortium. Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nature Genet. 2007 Mar; 39(3):319-28
  10. Ma DQ, Cuccaro ML, Jaworski JM, Haynes CS, Stephan DA, Parod J, Abramson RK, Wright HH, Gilbert JR, Haines JL, Pericak-Vance MA. Dissecting the locus heterogeneity of autism: significant linkage to chromosome 12q14. Mol Psychiatry. 2007 Apr; 12(4):376-84
  11. Xu PT, Li YJ, Qin XJ, Kroner C, Green-Odlum A, Xu H, Wang TY, Schmechel DE, Hulette CM, Ervin J,Hauser M, Haines J, Pericak-Vance MA, Gilbert JR. A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer Disease.Mol Cell Neurosci. 2007 Nov; 36(3):313-31.
  12. Cuccaro ML, Brinkley JS, Abramson RK, Hall A, Wright HH, Gilbert JR, Pericak-Vance MA. Autism in African American Families: Clinical-Phenotypic Findings. Am J Med Genet B Neuropsychiatr Genet. 2007 Dec 5; 144(8):1022-6.
  13. Liang X, Schnetz-Boutaud N, Bartlett J, Allen MJ, Gwirtsman H, Schmechel D, Carney R, Gilbert JR,
  14. Pericak-Vance MA, Haines JL. No Association between SNP rs498055 on Chromosome 10 and Late-Onset Alzheimer Disease in Multiple Datasets. Ann Hum Genet. 2008 Jan; 72(Pt 1):141-4.