Evadnie Rampersaud


rampersaud_9656_web resize.jpgEvadnie Rampersaud, M.S.P.H, PhD is a Research Assistant Professor in the Miami Institute for Human Genetics. Dr. Rampersaud is a genetic epidemiologist who is interested in the application of statistical methods to identify both genetic and environmental factors that influence risk to diseases including type 2 Diabetes (T2M), obesity, dilated cardiomyopathy, amyotrophic lateral sclerosis (ALS) and systemic lupus erythematosus (SLE). She is particularly interested in understanding the genetics of diseases that disproportionately affect women's health and in studying the role that maternal effects, genetic imprinting and maternal-fetal interactions play in causation of these disorders.




Contact Information
erampersaud@med.miami.edu
Assistant: Lili Tewes
Miami Institute for Human Genomics
1120 NW 14th Street
Miami, FL 33136
ph: 305-243-1192
fax: 305-243-2396

Selected Publications

  1. Allingham RR, Seo B, Rampersaud E, Bembe M, Challa P, Liu N, Parrish T, Karolak L, Gilbert J, Pericak-Vance MA, Klintworth GK, Vance JM. A duplication in chromosome 4q35 is associated with hereditary benign intraepithelial dyskeratosis. Am J Hum Genet. 2001 Feb;68(2):491-4.
  2. Scott WK, Nance MA, Watts RL, Hubble JP, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH Jr, Goetz CG, Small GW, Masterman D, Mastaglia F, Laing NG, Stajich JM, Slotterbeck B, Booze MW, Ribble RC, Rampersaud E, West SG, Gibson RA, Middleton LT, Roses AD, Haines JL, Scott BL, Vance JM, Pericak-Vance MA. Complete genomic screen in Parkinson disease: evidence for multiple genes. JAMA. 2001 Nov 14;286(18):2239-44.
  3. Speer MC, Melvin EC, Viles KD, Bauer KA, Rampersaud E, Drake C, George TM, Enterline DS, Mackey JF, Worley G, Gilbert JR, Nye JS; NTD Collaborative Group. Neural Tube Defects. T locus shows no evidence for linkage disequilibrium or mutation in American Caucasian neural tube defect families. Am J Med Genet. 2002 Jul 1;110 (3):215-8.
  4. Rampersaud E, Melvin EC, Siegel D, Mehltretter L, Dickerson ME, George TM, Enterline D, Nye JS, Speer MC; NTD Collaborative Group. Updated investigations of the role of methylenetetrahydrofolate reductase in human neural tube defects. Clin Genet. 2003 Mar;63(3):210-4.
  5. Rampersaud E, Allen A, Li YJ, Shao Y, Bass M, Haynes C, Ashley-Koch A, Martin ER, Schmidt S, Hauser ER. Adjusting for covariates on a slippery slope: linkage analysis of change over time. BMC Genet. 2003 Dec 31;4 Suppl 1:S50.
  6. Hauser ER, Hsu FC, Daley D, Olson JM, Rampersaud E, Lin JP, Paterson AD, Poisson LM, Chase GA, Dahmen G, Ziegler A. Effects of covariates: a summary of Group 5 contributions. Genet Epidemiol. 2003;25 Suppl 1:S43-9.
  7. Rampersaud E, Brusato C, Melvin EC, Speer MC, Metcalf K; NTD Collaborative Group. No evidence for heterozygote advantage at MTHFR in patients with lumbosacral myelomeningocele or their relatives. Genet Med. 2004 Jan-Feb;6(1):69-70.
  8. Rampersaud E, Scott WK, Hauser ER, Speer MC. Potential for expanded power in linkage studies using the ALLEGRO and MERLIN software programs. J Med Genet. 2005 Dec;42(12):e68.
  9. Rampersaud E, Bassuk AG, Enterline DS, George TM, Siegel DG, Melvin EC, Aben J, Allen J, Aylsworth A, Brei T, Bodurtha J, Buran C, Floyd LE, Hammock P, Iskandar B, Ito J, Kessler JA, Lasarsky N, Mack P, Mackey J, McLone D, Meeropol E, Mehltretter L, Mitchell LE, Oakes WJ, Nye JS, Powell C, Sawin K, Stevenson R, Walker M, West SG, Worley G, Gilbert JR, Speer MC. Whole genome-wide linkage screen for neural tube defects reveals regions of interest on chromosomes 7 and 10. J Med Genet. 2005 Dec;42(12):940-6.
  10. Stamm DS, Rampersaud E, Slifer SH, Mehltretter L, Siegel DG, Xie J, Hu-Lince D, Craig DW, Stephan DA, George TM, Gilbert JR, Speer MC. High-density single nucleotide polymorphism screen in a large multiplex neural tube defect family refines linkage to loci at 7p21.1-pter and 2q33.1-q35.Birth Defects Res A Clin Mol Teratol. 2006 Jun;76(6):499-505.
  11. Rampersaud E, Morris RW, Weinberg CR, Speer MC, Martin ER. Power calculations for likelihood ratio tests for offspring genotype risks, maternal effects and parent-of-origin (POO) effects in the presence of missing parental genotypes when unaffected siblings are available. Genetic Epidemiology. 2007. Jan;31(1):18-30.
  12. Rampersaud E, Damcott CM, Connell J, Fu M, Shen H, Shelton J, McArdle P Ying J, Shi X, Ott SH, , Zhang L, Zhao Y, Mitchell BD, Shuldiner AR. Identification of novel candidate genes for type 2 diabetes from a 100K genome-wide association scan in the Old Order Amish: Evidence for replication from diabetes-related quantitative traits and from independent populations. Diabetes. 2007 Dec;56(12):3053-62.
  13. Rampersaud E, Melvin EC, Speer MC. Chapter 15, Genetics of Non-syndromic neural tube defects. In : Neural Tube Defects: From origin to treatment. Oxford University Press.