Dale Hedges


Dale Hedges_web resize.jpgDale J. Hedges , Ph.D. is an Assistant Professor of Human Genetics and serves as the Assistant Director of the Center for Genome Technology. His primary research focuses on human transposable elements, including their relationship to human genetic diseases. Dr. Hedges' experience involves both molecular and bioinformatics based approaches to addressing biological questions.







Contact Information
dhedges@med.miami.edu
Miami Institute for Human Genomics
1120 NW 14th Street
Miami, FL 33136
ph: 305-243-6177
fax: 305-243-2396

Selected Publications
  1. Pericak-Vance MA, Grubber J, Bailey LR, Hedges D, West S, Santoro L, Kemmerer B, Hall JL, Saunders AM, Roses AD, Small GW, Scott WK, Conneally PM, Vance JM, Haines JL. Identification of novel genes in late-onset Alzheimer's disease. Exp Gerontol. 2000 Dec 35(9-10):1343-52.
  2. Wolpert CM, Donnelly SL, Cuccaro ML, Hedges DJ, Poole CP, Wright HH, Gilbert JR, Pericak-Vance MA. De novo partial duplication of chromosome 7p in a male with autistic disorder. Am J Med Genet. 2001April 8;105(3):222-5.
  3. Li YJ, Scott WK, Hedges DJ, Zhang F, Gaskell PC, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Allen FA Jr, Goetz CG, Mastaglia F, Stajich JM, Gibson RA, Middleton LT, Saunders AM, Scott BL, Small GW, Nicodemus KK, Reed AD, Schmechel DE, Welsh-Bohmer KA, Conneally PM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA. Age at onset in two common neurodegenerative diseases is genetically controlled. Am J Hum Genet. 2002 April; 70(4):985-93.
  4. Hedges DJ., Walker JA, Callinan PA, Shewale J.G., Sinha SK and Batzer MA A mobile element based assay for human gender determination. Analytical Biochemistry 2003 Jan 1; 312(1):77-9.
  5. Walker JA., Hughes DA, Hedges DJ, Anders BA, Laborde ME, Shewale JG, Sinha SK and Batzer MA Quantitative PCR for DNA identification based on genome specific interspersed repetitive elements. Genomics 2004 Mar; 83(3):518-27.
  6. Hedges DJ, Callinan PA, Cordaux R, Xing J, Barnes E, Batzer MA. Differential Alu mobilization and polymorphism among the human and chimpanzee lineages Genome Research 2004 June14(6):1068-75.
  7. Hedges DJ, Cordaux R, Xing J, Witherspoon DJ, Rogers AR, Jorde LB, Batzer MA. Modeling the amplification dynamics of human alu retrotransposons. PLoS Comput Biol. 2005 Sep;1(4):e44
  8. Cordaux R, Hedges DJ, Herke SW, Batzer MA. Estimating the retrotransposition rate of human Alu elements. Gene 2006 May 24; 373:134-7.
  9. Hedges DJ, Deininger PL. Inviting instability: Transposable elements, double-strand breaks, and the maintenance of genome integrity. Mutat Res. 2007 Mar 1; 616(1-2):46-59.
  10. Hedges, DJ, Deininger PL. Repetitive Elements and Human Disorders. Encyclopedia of Life Sciences (In Press).