Center for Models of Human DiseaseThe Center for Models of Human Disease Acting Director: Katherina Walz, Ph.D Overview of the Center: The Center for Models of Human Disease is projected as an integrated, multi-organism center that aspires to rapidly and simultaneously validate the previously found rare variants as disease causatives, to understand the biology related to these mutations and to create genetic and biology-based models that can be used as targets for therapeutic screening.
The ultimate goal of The Center for Models of Human Diseases is to articulate the discovery of genetic variants associated with a myriad of different human diseases with the biology underlying those mutations to accelerate the mechanistic understanding of novel disease genes. Right now we are utilizing Mus musculus as model in our center, with the following workflow: |
